Laboratory for the Analysis of Medicines

Publications

Publications

2022 Publications

In vitro/in vivo degradation analysis of trastuzumab by combining specific capture on HER2 mimotope peptide modified material and LC-QTOF-MS.

Lu L, Liu X, Zuo C, Zhou J, Zhang A, Fillet M, Crommen J, Jiang Z, Wang Q

Anal. Chim. Acta 2022 Sep 8; 1225:340199.

2022 Publications

Qualitative and quantitative comparison of different commercially available 1-84 parathyroid hormone proteins to the WHO international standard 95/646 using orthogonal methods.

Nyssen L, Fillet M, Cavalier E, Servais AC

J. Pharm. Biomed. Anal. 2022 Sep 20; 219:114942.

2022 Publications

Potential of single pulse and multiplexed drift-tube ion mobility spectrometry coupled to micropillar array column for proteomics studies.

Nix C, Cobraiville G, Gou MJ, Fillet M

Int. J. Mol. Sci. 2022 Jul 6;23(14):7497.

2022 Publications

Chapter 10-Microfluidics in three aspects of the drug development process: biomarker discovery, preclinical studies and drug delivery systems.

Nix C, Fillet M

In Multidisciplinary Microfluidic and Nanofluidic Lab-on-a-chip: Principles and applications 2022 pp.275-295.

2022 Publications

Improvement of chemo- and stereoselectivity for phosphothioate oligonucleotides in capillary electrophoresis by addition of cyclodextrins.

Ghassemi K M, Demelenne A, Crommen J, Servais AC, Fillet M

J. Chrom. A. 2022 Aug 2;1676:463270.

2022 Publications

Selection of essential spectra to improve the multivariate curve resolution of minor compounds in complex pharmaceutical formulations.

Coic L, Sacré PY, Dispas A, De Bleye C, Fillet M, Ruckebusch C, Hubert P, Ziemons É.

Anal Chim Acta. 2022 Mar 15;1198:339532.

2022 Publications

A pharmaceutical-related molecules dataset for reversed-phase chromatography retention time prediction built on combining pH and gradient time conditions

Van Laethem T, Kumari P, Hubert P, Fillet M, Sacré PY, Hubert C.

Data Brief. 2022 Mar 4; 42:108017.

2022 Publications

HPV infection alters vaginal microbiome through down-regulating host mucosal innate peptides used by Lactobacilli as amino acid sources.

Lebeau A, Bruyere D, Roncarati P, Peixoto P, Hervouet E, Cobraiville G, Taminiau B, Masson M, Gallego C, Mazzucchelli G, Smargiasso N, Fleron M, Baiwir D, Hendrick E, Pilard C, Lerho T, Reynders C, Ancion M, Greimers R, Twizere JC, Daube G, Schlecht-Louf G, Bachelerie F, Combes JD, Melin P, Fillet M, Delvenne P, Hubert P, Herfs M.

Nat Commun. 2022 Feb 28;13(1):1076.

2022 Publications

Separation of phosphorothioated oligonucleotide diastereomers using multiplexed drift tube ion mobility mass spectrometry.

Demelenne A, Nys G, Nix C, Fjeldsted JC, Crommen J, Fillet M.

Anal Chim Acta. 2022 Jan 25;1191:339297.

2021 Publications

Comparison of Three Complementary Analytical Techniques for the Evaluation of the Biosimilar Comparability of a Monoclonal Antibody and an Fc-Fusion Protein.

Demelenne A, Ben Yahia A, Lempereur D, Crommen J, Servais AC, Fradi I, Fillet M.

Front Chem. 2021 Dec 6;9:782099.